Assessment Of Adrenal Suppression Induced By Betamethasone In Woman At Risk For PrematureDelivery Shariati Hospital (2001-2002)
| Autor: | Eslamian L, Yar Ahmadi S, Adineh M |
|---|---|
| Jazyk: | perština |
| Rok vydání: | 2003 |
| Předmět: | |
| Zdroj: | Tehran University Medical Journal, Vol 61, Iss 2, Pp 115-118 (2003) |
| ISSN: | 1735-7322 1683-1764 |
| Popis: | Betamethason Causes adrenal suppression in woman at risk of pre¬term delivery."nMaterials and Methods: An interventional study was done on 25 women at risk of pre-term delivery, Betamethason course (12-mg-im q 24 hr for 2 doses) was prescribed for 2 consecutive weeks. ACTH Stimulation test was done one week after each Betamethason injection. (1st between 30-31 w and the 2nd one week later. Serum Cortisol levels were measured before betamethason administration and then before and 30 minutes after ACTH Stimulation test."nResults: All Subjects had normal baseline Cortisol level. Mean baseline serum Cortisol levels decreased with each ACTH stimulation test from 24.32±0.77 ug/dl ( before Betamethason) to 7.33±1.73 ug/dl ( one week after the second course of Betamethasone) (p < 0.0001). The mean stimulated Cortisol levels also decreased from 23.93±1.44, ug/dl (befor Betamathason) to 19.53=+2.69 (one week after the second course of Betamethasone) (P |
| Databáze: | OpenAIRE |
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