| Autor: |
Sultan Nacak, Berna Özçelik, Serdar Ünlü, M. Fethi Sahin, Semiha Özkan, Ufuk Abbasoglu |
| Jazyk: |
angličtina |
| Rok vydání: |
2005 |
| Předmět: |
|
| Zdroj: |
Turkish Journal of Pharmaceutical Sciences, Vol 2, Iss 1, Pp 25-33 (2005) |
| ISSN: |
2148-6247 |
| Popis: |
A series of novel Mannich bases of 7-acyl-5-chloro-2-oxo-3H-benzoxazoles were synthesized by reacting them with formaldehyde and several seconder amine derivatives. Their chemical structures were elucidated by means of their IR, 1H-NMR data and by elemental analysis. Investigation of in vitro antimicrobial activity of compounds was done by broth microdilution method against six pathogenic bacteria. Özet 7-Açil-5-Kloro-2-Okso-3H-Benzoksazollerin mannich bazlari, bu türevlerin formaldehit ve birkaç sekonder amin türevleriyle tepkimeye sokulmasiyla sentezlenmistir. Kimyasal yapilari, IR, 1H-NMR ve elementel analiz verileriyle kanitlanmistir. Bilesiklerin in vitro antimikrobiyal aktivitelerinin incelenmesi, alti patojenik bakteriye karsi broth mikrodilisyon yöntemi kullanilarak yapilmistir. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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