Effect of Ciprofloxacin and Granulocyte Colony Stimulating Factor in Bactericidal Activity of Polymorphonuclear Leukocytes Against Pseudomonas aeruginosa

Autor: Ayşegül ESKİTÜRK, Ülkü ERGİN
Jazyk: angličtina
Rok vydání: 1998
Předmět:
Zdroj: Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi, Vol 3, Iss 1, Pp 26-30 (1998)
Popis: The in vitro effect of subinhibitory and inhibitory concentrations of ciprofloxacin and G-CSF on the bactericidal activity of polymorphonuclear leukocytes (PMNL) against Pseudomonas aeruginosa was investigated. PMNL obtained from healthy volunteers were incubated with different concentrations of G-CSF and ciprofloxacin for 180 min. Although G-CSF showed certain amount of bactericidal effect, this was statistically insignificant when compared with bactericidal activity of PMNL: The minimum inhibitory concentration of ciprofloxacin as well as subinhibitory concentration enhanced the bactericidal activity of PMNL (p
Databáze: OpenAIRE