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Objective: To discuss Vitamin C combined with statins atorvastatin calcium affect oxidative stress in hemodialysis patients with micro-inflammatory state. Methods: 92 hemodialysis patients admitted to hospital were randomly divided into atorvastatin calcium group (A) and vitamin C combined with atorvastatin calcium group (group B), select the same period and 30 healthy volunteers as group C, compare three groups before and after treatment with the microinflammatory state of oxidative stress indexes, including malondialdehyde (MDA), superoxide dismutase (SOD), C-reactive protein (CRP), interleukin-6 (IL-6), tumor necrosis factor (TNF-α) levels in the case. Results: Group A Group B and MDA levels before treatment were significantly higher than group C, after treatment indicators were significantly lower than before treatment, and group B index level change is more significant, the difference was statistically significant (P |