Oxidative stress and antioxidant defences – a pedagogical review

Autor: Ana Sofia Fernandes, Matilde Castro, Nuno Guerreiro Oliveira
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Journal Biomedical and Biopharmaceutical Research (BBR), Vol 8, Iss 1, Pp 97-108 (2011)
ISSN: 2182-2379
2182-2360
Popis: tIn the last years a growing interest concerning the effects of oxidative stress has been noticed and its involvement in different pathological phenomena suggested by many scientific evidences. The present paper aims to review oxidative stress basic concepts and antioxidation, introducing health professionals and students to this topic. Thus, main reactive oxygen species generation pathways and lipid peroxidation processes are addressed under this view. This paper focus antioxidation defenses, superoxide dismutases, catalase and glutathione peroxidases in particular, enzymes playing a pivotal role in this cellular context. The present review also mentions the oxidative stress deleterious effects and pathologies wher oxidative damage is involved, justifying the interest of antioxidative compounds.
Databáze: OpenAIRE