Microsurgical removal of brainstem cavernoma: A report of 42 cases

Autor: Jian-ning ZHANG, Ya-ming WANG, Gang CHENG, Zhi-chao LI, Xin YU, Hong-wei WANG, Quan-jun ZHAO, Hu-lin ZHAO, Wang-sheng LU, Rui LIU, Feng YIN, Zeng-min TIAN
Jazyk: čínština
Rok vydání: 2012
Předmět:
Zdroj: Medical Journal of Chinese People's Liberation Army, Vol 37, Iss 8, Pp 630-634 (2012)
ISSN: 0577-7402
Popis: Objective To summarize the clinical features and the surgical approach and techniques for microsurgical removal of brainstem cavernoma, and to evaluate the efficacy of surgical treatment of brainstem cavernoma. Methods The clinical data of 41 brainstem cavernoma patients treated by microsurgical resection from January 2003 to April 2011 were retrospectively analyzed, and they were 23 males and 18 females, aged 8 to 62 years. The clinical presentations included signs and symptoms of increased intracranial pressure, such as headache and dizziness, long-tract signs such as cranial nerve dysfunction, numbness and decrease in muscle strength, and ataxia. According to the site of the lesions, surgical approaches were selected following the principle of "the shortest distance between the incision and the lesion". Intraoperative short-latency somatosensory evoked potential (SSEP) and auditory evoked potential (AEP) were monitored. Results Total resection of cavernoma was achieved in 35 patients, small residual tumor was left in 6 with giant lesions. No death occurred. Twenty-seven patients showed improvement in nerve function. Aggravation of pre-existing neurological disorders or appearance of new neurological disorders was found in 14 patients, including 2 with respiratory dysfunction who regained spontaneous breathing after assisted respiration for one week. Follow-up was carried out for 38 months in average. Neurological deficits have been restored in most patients, and no recurrence was found except for 1 case of re-bleeding from residual tumor. Conclusions According to the lesion site and protruding direction, individualized surgical approach can be selected following the "shortest distance" principle for the resection of brainstem cavernoma. The application of intraoperative navigation and electrophysiological monitoring of the brainstem is helpful in reducing surgical injury and decreasing the complications.
Databáze: OpenAIRE