Selenium and Diazinon Neurotoxicity after an Intraperitoneal Administration in Rats

Autor: Robert Toman, Svätoslav Hluchý, Nora Maruniaková, Zuzana Hajková
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Scientific Papers Animal Science and Biotechnologies, Vol 46, Iss 2, Pp 166-170 (2013)
ISSN: 2344-4576
1841-9364
Popis: The purpose of this study was to evaluate the effect of selenium, diazinon and the mixture of diazinon with selenium on rat serum cholinesterase activity after an intraperitoneal administration. Forty rats were divided into three experimental and one control groups. Animals in the first group were dosed with selenium (2 mg/kg b.w.), in the second group with diazinon (20 mg/kg b.w.) and in third group with simultaneous administration of diazinon and selenium in the same doses as in the individual dosage intraperitoneally. Catalytic activity of cholinesterase was determined 36 hours after the compounds administration. A significat decreases (P
Databáze: OpenAIRE