Retrospective Evaluation of Cases with the Diagnosis of Acute Bacterial Meningitis Over a 33-Year Period

Autor: Hüsrev DİKTAŞ, Mustafa HATİPOĞLU, Vedat TURHAN, Ali ACAR, Oral ÖNCÜL, Nafiz KOÇAK, Levent GÖRENEK
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi, Vol 17, Iss 4, Pp 161-166 (2012)
Popis: Introduction: In this study, we retrospectively evaluated the epidemiological and clinical features, risk factors, laboratory findings, and relations between the therapy duration and mortality rates of cases followed with the diagnosis of acute bacterial meningitis. Materials and Methods: We reviewed data of patients with acute bacterial meningitis admitted to our hospital over a period of 33 years (1977-2010). Clinical, laboratory and demographic data were collected from the official records retrospectively. The data were analyzed through SPSS (Statistical Package for the Social Sciences), version 15.0. Results: One hundred and two of (97.2%) 110 cases were male and 8 (7.3%) were female, and the average age was 22.5 ± 5.93 (minimum 14, maximum 59). Recurrent meningitis had been seen in 10 (9.1%) cases. First admission to the hospital was 3.5 ± 4.1 days after the onset of complaints. While the most important physical examination findings were fever (91.8%), neck stiffness (95.5%) and Kernig’s and Brudzinski signs (84.5%), the most common neurologic sign was confusion (64.5%). In the microbiological analysis of the cerebrospinal fluid, pathogens were determined in 40% of all cases with Gram stain. While 75% of those showed gram-negative morphology, 25% showed gram-positive coccus morphology. Cultivation was detected in 27.3% of cerebrospinal fluid cultures. Conclusion: For acute bacterial meningitis diagnosis, Gram stain examination of cerebrospinal fluid is very important as well as clinical findings and physical examination.
Databáze: OpenAIRE