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Aim: To interpret microscopic findings in the placental villi of a late fetal stillbirth Material and Methods: A placenta associated to idiopathic fetal death at 34 weeks' gestation, weighing 630 g and obtained from a cesarean preterm delivery was considered for microscopic analysis. Five specimens of placental villi were obtained from the studied placenta, subsequently processed for Haematoxylin - Eosin staining and finally observed in a Zeiss microscope with 10X and 40X objectives (20 fields/slide). The following features were considered for microscopic analysis: villous maturity, fibrinoid deposits, villous edema, stromal fibrosis, calcification, syncytial nodules, intervillous thrombosis, infarction, hyperplasia of the muscular media and congested vessels Results: Infiltration of mononuclear cells was observed in decidua but not in placental villi. Studied placenta showed a low ramification of villi. Abundant immature intermediate villi revealed a noticeable immaturity. Edema, calcification, invasion of endothelial cells to lumen of vessels in stem villi, prominent cytotrophoblast and fibrosis were also found. Conclusion: Severe degenerative changes affecting the maturity of placental villi, as low ramifications, interacting with edema, infection and a possible decrease in utero-placental blood flood could constitute events contributing to the fetal death here reported and analyzed. |
