Comparison of Ultrasonography (USG), Mangnetic Resonance Imaging (MRI), Computed Tomography (CT) and Fine Needle Aspiration Biopsy (FNAB) for the Diagnosis of Salivary Gland Tumor

Autor: Ahmet Doblan, Ergün Sevil, Togay Müderris, Muzaffer Kırış
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Dicle Medical Journal, Vol 47, Iss 4, Pp 911-919 (2020)
ISSN: 1308-9889
1300-2945
Popis: Objective: The determination of preoperative differences between benign and malignant neoplasms in salivary gland tumors is important in determining the necessity, urgency and scope of surgical operation. The aim of this study was to determine the descriptive characteristics of salivary gland tumors and the diagnostic value of diagnostic methods in patients operated for salivary gland mass. Methods: The study is a descriptive study performed retrospectively with the medical records of patients operated for malignant or benign mass in salivary glands between 2008-2016. Preoperative Ultrasonography (US), Magnetic Resonance Imaging, Computed Tomography (CT), Fine Needle Aspiration Biopsy (FNAB) and postoperative histopathological results were evaluated. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) calculations were used for the used diagnostic methods and each was expressed as a percentage (%). Sensitivity, specificity, positive predictive value (PPD), negative predictive value (NPD), area under the curve±standard error (AUC ± SE) values of the diagnostic methods were used for ROC analysis. Results: The study group consisted of 114 individuals with a mean age of 46.90 ± 14.32 years. The most common localization of salivary gland tumors was parotid gland (71.9%). Histopathological examination of the patients for diagnostic purposes revealed that 11.4% had malignant tumors. Pleomorphic adenoma was the most common benign tumor and mucoepidermoid cancer was the most common malignant tumor. The highest sensitivity, NPD, AUC ± SE values were MRI and the method with the highest specificity and PPD was FNAB. Conclusion: In conclusion, it was found that salivary gland tumors were most commonly seen in the parotid gland (11.4% malignant), the most common benign salivary gland tumor was pleomorphic adenoma and the most common malignant salivary gland tumor was mucoepidermoid cancer. The method with the highest sensitivity, NPD, AUC ± SE values was MRI and the method with the highest specificity and PPD was FNAB. It was thought that clinical studies in larger samples that examined the diagnostic values of USG, CT, MRI, FNAB in salivary gland tumors would be beneficial.
Databáze: OpenAIRE