| Popis: |
Objective To evaluate the efficacy of zero profile anterior cervical interbody fixation system (ZPFS) and traditional cervical plate internal fixation for the treatment of cervical spondylosis using a meta-analysis. Methods Related literature was collected by computerized search of online databases including PubMed, Embase, Cochrane Library, CNKI, VIP, and Wanfang and by manual search of the series of Chinese Medical Journals (2008.2-2018.4). Papers that reported controlled trials of ZPFS and cervical plate internal fixation for the treatment of cervical spondylosis were enrolled in this study. The quality of trials was strictly assessed. RevMan5.3 software provided by the Cochrane Collaboration was used for the analysis of data. The eight indexes included operation time, intraoperative bleeding volume, postoperative JOA score, postoperative VAS score, intervertebral height, dysphagia rate, ossification of anterior longitudinal ligament rate, and neck disability index (NDI). Results Thirty-two papers (12 Chinese and 20 English studies) involving 2154 patients (1044 in ZPFS group and 1110 in cervical plate internal fixation group) were finally enrolled. According to the meta-analysis, compared with cervical plate internal fixation, ZPFS had a significantly lower rate of dysphagia (OR=0.36, 95%CI: 0.28 to 0.47, P0.05). In terms of operation time and intraoperative bleeding volume, the descriptive analysis was adopted in the study due to the heterogeneity among the studies. Further study is needed. Conclusions Compared with the traditional cervical plate internal fixation, ZPFS has the advantages as lower incidence of dysphagia and ossification of the anterior longitudinal ligament, while it has the same effect as the traditional cervical plate internal fixation in the aspect of the JOA score, the VAS score, NDI and the intervertebral height. DOI: 10.11855/j.issn.0577-7402.2018.11.09 |
