| Popis: |
The aim of the research – to carry out an analytical review of modern sources of scientific literature covering the issues of screening, treatment and prevention of complications in pregnant women with hepatitis C. Materials and methods. The analysis of 56 domestic and foreign sources of literature on this topic. Results. According to the scientific analysis, new data on the prevalence of hepatitis C in pregnancy in the Russian Federation and in the world have been obtained. The review describes possible complications of pregnancy and childbirth associated with hepatitis C, assessed the risk of vertical transmission of infection, highlighted the effectiveness of screening this disease and the tactics of managing pregnancy in infected women. Conclusion. The high prevalence of hepatitis C in pregnancy makes it an urgent problem. The analysis shows that prompt delivery of pregnant women with hepatitis C does not reduce the risk of vertical transmission, and therefore cannot be recommended, while prohibiting early amniotomy, preventing a prolonged anhydrous period, reducing the frequency of invasive fetal monitoring and episiotomy are effective ways to prevent fetal infection and newborn. Modern antiviral therapy with direct antiviral drugs has revolutionized the treatment of hepatitis C, but drugs that allow to cure the disease during pregnancy are under development and clinical studies. |
