| Autor: |
Bába László-István, Kolcsár Melinda, Gáll Zsolt, Bencze László Csaba, Man Adrian, Kun Imre Zoltán |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Acta Medica Marisiensis, Vol 67, Iss 1, Pp 60-66 (2021) |
| ISSN: |
2247-6113 |
| Popis: |
Objective: Atypical antipsychotics (AAPs) often cause metabolic adverse effects (mAE) such as weight gain and dyslipidemia. The mechanisms underlying AAP induced mAE are not fully elucidated. The endocannabinoid system (ECS) is a key system in the regulation of energy metabolism that may be involved in AAPs induced mAE. In this experiment, we studied the expression of three major components of ECS: cannabinoid receptor 1 (CB1), fatty acid amidohydrolase (FAAH) and monoacyl glycerol lipase (MAGL) after chronic administration in rat of three AAPs: olanzapine (Ola), aripiprazole (Ari) and cariprazine (Car). |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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