| Autor: |
Jing-Du Tian, Chuan Liu, Jie Yang, Xu-Bin Gao, Ji-Hang Zhang, Xiao-Hui Zhao, Lan Huang |
| Jazyk: |
čínština |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Medical Journal of Chinese People's Liberation Army, Vol 45, Iss 12, Pp 1248-1253 (2020) |
| ISSN: |
0577-7402 |
| Popis: |
Objective To explore the incidence of fatigue symptoms and the relationship with pulmonary artery pressure in healthy people who acutely rush into high altitude (HA) areas. Methods A hundred and thirty-six healthy subjects (young men) were recruited during June to July 2013, and transported from Chongqing C. (asl. 400 m) to Litang Co. (asl. 4100 m) by bus. The physiological parameters of subjects were collected before and after entering the plateau, the heart function and the hemodynamic indexes of pulmonary circulation were detected by echocardiography. The subjects were divided into fatigue⁺ group (n=78) and fatigue⁻ group (n=58) according to their degree of fatigue evaluated with Fatigue Assessment Scale. The changes of the above indicators were compared before and after entering the plateau and between the two groups of subjects. Logistic regression analysis was performed to screen the related risk factors of plateau fatigue. Results Following acute high altitude exposure, the mean pulmonary arterial pressure (mPAP), pulmonary artery systolic pressure (sPAP) and pulmonary vascular resistance (PVR) in subjects increased obviously. Compared with fatigue⁻ group, the mPAP, sPAP and PVR increased significantly in fatigue⁺ group [17.9 mmHg vs. 20.6 mmHg; 26.1 mmHg vs. 30.4 mmHg; and 4.41 Woods vs. 5.56 Woods], and more larger right ventricular end diastolic area (RVEDA) [(22.0±3.8) cm² vs. (20.5±3.6) cm²], right ventricular end systolic area (RVESA) [(13.1±2.7) cm² vs. (12.1±2.3) cm²] and transverse diameter of right ventricular base [(3.92±0.45) cm vs. (3.72±0.41) cm] were in fatigue+ group than those in fatigue– group with statistical significance (P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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