PRINCIPLES OF DIAGNOSTIC AND TREATMENT IN CERVICAL NEOPLASIA

Autor: Eduard Crauciuc, Mariana Bratu, Eugen Ungureanu, Ovidiu Toma, Dragos Crauciuc
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Analele Ştiinţifice Ale Universităţii Alexandru Ioan Cuza din Iași,Sectiunea II A : Genetica si Biologie Moleculara, Vol 15, Iss 2, Pp 46-50 (2016)
ISSN: 2248-3276
1582-3571
Popis: According to the World Health Organization, cervical cancer ranks second in cancer in women, after breast cancer, as it represents 44% of the total feminine genital cancers. Every year 460,000 women all over the world are diagnosed with invasive cervical cancers and 200,000 women die by this illness. According to the data supplied by the Center for Health Statistics in Romania, over 66% of the new cases of cancer detected are between 35 and 55 years old, and about 70% of the deaths caused by cervical cancer is recorded for the women between 45 and 70 years old. The study was performed on a number of 1885 women aged between 20 and 85 years old, detected with cervical neoplasia in different stages in the County Hospital Galaţi. The cases studied showed a prevalence of cervical cancer of 37.3%. The profile of the patient showed that they come mainly from the urban area (77.3%), that about 80% of these women have a reduced educational level, and 23,6% are unemployed. The detected risk factors are: age, marital status, smoking, coffee consumption, alcohol, sex life debut, associated chronic diseases (high blood pressure, obesity), and contraceptives. In order to establish the diagnostic of cervical neoplasia the following examinations were performed: cytological smear, colposcopic examination, biopsy, histopathologic and complementary examinations. The comparison of the diagnostic methods allowed the doctors to establish how effective each of the conduct options is in the early detection of the serious changes, as these changes can progress towards cancer. They also wanted to see how acceptable every conduct option for the patients is; what is the cost/efficiency ratio for each option. The diagnostic certainty was accomplished through a histo-pathological examination of the material obtained by biopsy in comparison with colposcopy, with an accuracy of the method of 50.1%. We consider that patients with cervical cancer must not be abandoned, regardless of the stage of the cancer when they come to see the doctor, because sometimes, after a well-conducted complex treatment, the cases had a satisfactory evolution.
Databáze: OpenAIRE