| Autor: |
Eric René Sieliatchom Nkanwen, , , , and, Maurice Ducret Awouafack, Jean Jules Kezetas Bankeu, Hippolyte Kamdem Wabo, Sufyan Awad Alkarim Mustafa, Muhammad Shaiq Ali, Marc Lamshöft, Muhammad Iqbal Choudhary, Michael Spiteller, Pierre Tane |
| Jazyk: |
angličtina |
| Rok vydání: |
2013 |
| Předmět: |
|
| Zdroj: |
Records of Natural Products, Vol 7, Iss 4, Pp 296-301 (2013) |
| ISSN: |
1307-6167 |
| Popis: |
A trans cinnamic anhydride (1) isolated for the first time from a natural source, along with the known compounds: ferrulic acid (2), (E) p-hydroxy cinnamic acid (3), clovanediol (4), squalene (5), and α -bisabolene (6) were isolated from the stem bark of Cinnamomum zeylanicum. Their structures were elucidated by interpretation of NMR and MS data, and by comparison of these data with those reported in the literature. Their inhibitory properties were evaluated against Plasmodium falciparum enoyl-ACP reductase (PfENR) enzyme. Compounds 1 , 5 and 6 showed moderate inhibitory activity against P. falciparum enoyl-ACP reductase (PfENR) enzyme. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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