Complement factors in Acute Myocardial Infarction and Unstable Angina

Autor: mehrdad Namdari, ali Esmaili, babak Baharvand, sedighe Nadri, sasan Saket, mohammad javad Tarrahi, yaghob Shirkani, asghar Sepahvand
Jazyk: perština
Rok vydání: 2006
Předmět:
Zdroj: Yafteh, Vol 7, Iss 1, Pp 23-29 (2006)
ISSN: 1563-0773
Popis: Background: Coronary artery disease (CAD) is one of the most important and lethal diseases in the world. CAD represents a board spectrum of disease from silent ischemia at one end to sudden cardiac death at the other end. The middle of this spectrum consists of acute myocardial infarction (AMI) and unstable angina pectoris (UA). Recent data show that the inflammatory process plays a major role in the pathogenesis of acute coronary syndrome. In this study we evaluated the difference in complement factors C3 and C4 between AMI and UA, and the relation between early completions of AMI and UA and the amount of C3 and C4. Materials and methods: In this cross – sectional analytic study, 30 patients with AMI and 30 patients with UA were compared with healthy subjects. Clinical and laboratory data were collected. Blood samples were obtained on arrival and at 12.24 and 48 hours. electrocardiography and echocardiography were performed. All patients were monitored for 14 days after discharging from hospital. For all patients ECG was take on arrival and then daily bat. Findings: Complement activation occurred in patients with AMI and UA. In AMI activation of complement factors was significantly higher than in UA (p
Databáze: OpenAIRE