| Popis: |
Hepatic fibrosis (HF) is the common pathological basis of all chronic liver diseases, and is a necessary stage for the development of chronic liver disease into cirrhosis. The pathogenesis of liver fibrosis is very complicated. Different cells and cytokines play a major role in the pathogenesis of liver fibrosis. This article focuses on the development mechanism of liver fibrosis, different cells and cytokines (macrophages, natural killer cells, natural killer T cells, tumor necrosis factor, IL-22, transforming growth factor-β, connective tissue growth factor, vascular endothelial growth factor ) Its impact on the development of liver fibrosis is reviewed. |
