Study of metallo-β-lactamase production in clinical isolates of Pseudomonas aeruginosa

Autor:	Agrawal G, Lodhi R, Kamalakar U, Khadse R, Jalgaonkar S
Jazyk:	angličtina
Rok vydání:	2008
Předmět:	Pseudomonas aeruginosa lcsh:QR1-502 chemical and pharmacologic phenomena ceftazidime bacterial infections and mycoses lcsh:Microbiology Metallo-β-lactamase imipenem
Zdroj:	Indian Journal of Medical Microbiology, Vol 26, Iss 4, Pp 349-351 (2008)
ISSN:	1998-3646 0255-0857
Popis:	A study of metallo-β-lactamase (MBL) production was done in clinical isolates of Pseudomonas aeruginosa . Isolates resistant to ceftazidime and imipenem were screened for MBL production by double disc synergy test (DDST) and minimum inhibitory concentration reduction test. There was complete correlation between two methods for imipenem. For ceftazidime, there was correlation between the two methods in all except four strains. In the screening test for MBL, ceftazidime - EDTA combination was better than imipenem - EDTA combination. 8.05% strains were MBL producers. Presence of MBL producer P. aeruginosa is a cause of concern. Simple DDST can be helpful for monitoring of these emerging resistant determinants.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doajarticles::4dc0757cd8de5cbfda558b0634c66e17 http://www.ijmm.org/article.asp?issn=0255-0857 Zobrazit plný text záznamu Full Text from ScienceDirect