Studies on Antigenotoxic Effect of Piper betle Leaves

Autor:	Swati Dhote, P. Uma Devi, A. K. Pathak, R. B. Goswami
Jazyk:	angličtina
Rok vydání:	2007
Předmět:	anti-genotoxic activity piper betle gamma irradiation cyclophosphamide lcsh:RZ409.7-999 lcsh:Miscellaneous systems and treatments
Zdroj:	Journal of Natural Remedies, Vol 7, Iss 2, Pp 247-251 (2007)
ISSN:	2320-3358 0972-5547
Popis:	Objective: To study the antigenotoxic effect of Piper betle leaves in Gamma irradiation and Cyclophosphamide treated animals. Materials and methods: Swiss albino mice were given 50% methanolic extract (100mg/kg body weight.) of Piper betle leaves and antigenotoxic effect was studied after whole body gamma irradiation (4Gy) & cyclophosphamide (50mg/kg body weight.) treatment. Bone marrow protection was studied by scoring aberration in metaphase chromosomes. Results: No drug toxicity was observed at given dose (100mg/kg body weight.) Methanol extract ½ hr prior to irradiation protects animals against Gamma irradiation & Cyclophosphamide treatment.
Databáze:	OpenAIRE
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