Leg ulcers due to hyperhomocysteinemia
| Autor: | Krupa Shankar D, Akhib Syed |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2006 |
| Předmět: | |
| Zdroj: | Indian Journal of Dermatology, Venereology and Leprology, Vol 72, Iss 5, Pp 367-369 (2006) |
| ISSN: | 0973-3922 0378-6323 |
| Popis: | Chronic leg ulcers are rare in young adults and generally indicate a vascular cause. We report a case of a 26-year-old man with leg ulcers of eight months duration. Doppler study indicated venous incompetence and a postphlebitic limb. However, as the distribution and number of ulcers was not consistent with stasis alone and no features of collagen vascular disease were noted, a hyperviscosity state was considered and confirmed with significantly elevated homocysteine level in the serum. Administration of vitamins B1, B2, B6 and B12, trimethyl-glycine, mecobalamine, folic acid and povidone iodine dressings with culture-directed antibiotic therapy led to a satisfactory healing of ulcers over a period of one month. Hyperhomocysteinemia must be considered in the differential diagnosis of leg ulcers in young individuals. |
| Databáze: | OpenAIRE |
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