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In recent years, the synthesis of cerium oxide nanoparticles(CeO2NPs) and their application in biomedicine, especially in cancer treatment, have attracted wide attention from scientists. On the one hand, with obvious cytotoxicity to cancer cells, CeO2NPs can be used in photodynamic therapy(PDT), chemotherapy(CHT), etc, and can make cancer cells sensitive to radiotherapy(RT). On the other hand, CeO2NPs can protect normal cells and have antioxidant activity. The material with differential cytotoxicity provides a new idea for the development of cancer treatment reagents. The synthesis of CeO2NPs in recent years and the research progress in cancer treatment are summarized. |
