| Autor: |
Lydia Salhi, Samia Bouzroura-Aichouche, Yamina Benmalek, Yamina Bentarzi, Sophie Poulain-Martini, Bastien Cacciuttolo, Elisabet Dunach, Bellara Nedjar-Kolli |
| Jazyk: |
angličtina |
| Rok vydání: |
2013 |
| Předmět: |
|
| Zdroj: |
Organic Communications, Vol 6, Iss 2, Pp 87-94 (2013) |
| ISSN: |
1307-6175 |
| Popis: |
Starting from maleimide derivatives, a series of 2-thioxoimidazolidinones was prepared through two different procedures. These syntheses have achieved in two steps via reaction between maleimide derivatives 1,semicarbazide hydrochloride 9 and isothiocyanates5,the best results being obtained under acid conditions (AcOH or heteropolyacid in ethanol or acétonitrile). The synthesized compounds 11a-f and substituted thiohydantoins 6a-h, 8a-h were screened for their in vitro anti-bacterial activity against four bacterial strains. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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