The Effect of Bleomycin to the Mitotic Index who were Exposed to Radiation Chronically
| Autor: | Hilmi İsi, Diclehan Öktüren Oral, Ayşegül Bengisu Türkyılmaz, Mahmut Balkan |
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| Jazyk: | angličtina |
| Rok vydání: | 2004 |
| Předmět: | |
| Zdroj: | Dicle Medical Journal, Vol 31, Iss 2, Pp 4-8 (2004) |
| ISSN: | 1308-9889 1300-2945 |
| Popis: | Beginning with the therapeutic dose and increasing three differentdoses and three different periods of time Bleomycin (Bleomycin 0.3 μg/ml, 3μg/ml and 30 μg/ml, 6, 24, 48 hours) were added to blood which was beingcultured on 5 samples who were exposed to radiation chronically.The mitotic index in the lymphocyte culture was determined by means ofcounting 1000 cells from preparations belong to control and experimentgroups.The mitotic index was showed difference value to the differencebleomycin dose and the between difference samples. As the mitotic indexvalue (Per 1000 cell) 10.86 for the control group, this value fall to 8.73 at0.3 μg/ml, 5.0 at 3 μg/ml and 3.93 at 30 μg/ml. There were no significantdifferences between control group and 0.3 μg/ml, 3 μg/ml and 30 μg/ml(P>0.05). An important fall was seen between control group and 3 μg/mland 30 μg/ml, 0.3 μg/ml group and 3 μg/ml, 30 μg/ml (P |
| Databáze: | OpenAIRE |
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