Autor: |
Yong-Xia Wang, Yan-Ni Huang, Guo-Jun Li, Ting-Ting Ge, Cheng Chang, Hua Pei, Wen Yang, Ying-Zi Lin |
Jazyk: |
angličtina |
Rok vydání: |
2016 |
Předmět: |
|
Zdroj: |
Journal of Hainan Medical University, Vol 22, Iss 19, Pp 1-4 (2016) |
ISSN: |
1007-1237 |
Popis: |
Objective: To explore the antiviral activity on HSV-1 of the extracellular polysaccharides (EPS) purification of Paecilomyces lilacinus (P. lilacinus) isolated from mangrove in Hainan province. Methods: The toxicity of the EPS purification on Vero cells and its anti-HSV-1 activity were assessed by cytopathic effect(CPE) and MTT assay. The Vero cells survival rates, HSV-1 inhibition rates by the purification and virus titer were calculated. Results: The purification showed little cytotoxic effect on Vero with a CC50 value of 735.49 µg/mL. It could inhibit HSV-1 absorption on Vero cells, and there was a significant difference (P |
Databáze: |
OpenAIRE |
Externí odkaz: |
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