| Autor: |
Nisar Ahmad Khan, Dinesh Kumar, Zulfiqar Ali Bhat, Vijender Kumar, Navneet Nagpal and Santosh S. Bhujbal |
| Jazyk: |
angličtina |
| Rok vydání: |
2010 |
| Předmět: |
|
| Zdroj: |
Bangladesh Journal of Pharmacology, Vol 5, Iss 2, Pp 89-91 (2010) |
| ISSN: |
1991-0088 |
| Popis: |
In the present study, methanolic extract of tuber of Stephania glabra was evaluated for H1-bloker activity by employing in vitro screening models of guinea pig ileum and goat tracheal chain preparation. Goat isolated trachea and guinea pig ileum contracted to histamine in a dose-dependent manner while chlorpheniramine blocked this effect. The methanolic extract produced significant dose-dependent H1-receptor antagonist activity by blocking histamine-induced contraction. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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