Meningococcal polyvaccine on the basis of cleared IgAI protease
| Autor: | A P Alliluev, I V Anohina, L D Rumsh, O V Kotelnikova, E Yu Drozzina, L S Zhigis, E Yu Yagudaeva, O A Razgulyaeva, S S Zueva, L V Kozlov, A M Bichucher, A E Avakov |
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| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: | |
| Zdroj: | RUDN Journal of Medicine, Vol 0, Iss 1, Pp 7-12 (2010) |
| ISSN: | 2313-0261 2313-0245 |
| Popis: | IgA1-protease allocated from the culture N. meningitidis serogroup A. As original materials were used three different intermediate products of vaccine production: cultural fluid, cetavlon supernatant and cetavlon precipitate. IgA1-protease was used to evaluate their protectivity and immunogenity. It was shown, that isolated IgA1 protease from the meningococcus serogroup A is able to protect mice, infected by meningococcus serogroup B. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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