Detection of the ATP value and subgroup count of CD4+ T cell in patients with liver cancer recurrence after liver transplantation: its clinical significance

Autor: Jia-Yong Dong, Fei Teng, Wen-Yuan Guo, Xiao-Min Shi, Zhi-Ren Fu, Guo-Shan Ding, Jing-Hui Yang
Jazyk: čínština
Rok vydání: 2020
Předmět:
Zdroj: Medical Journal of Chinese People's Liberation Army, Vol 45, Iss 6, Pp 623-626 (2020)
ISSN: 0577-7402
Popis: Objective To explore the clinical significance of detecting CD4+ T cell ATP and subgroup count in patients with liver cancer recurrence after liver transplantation. Methods From November 2015 to November 2018, 84 patients with primary liver cancer underwent orthotopic liver transplantation in Shanghai Changzheng Hospital were selected and then divided into recurrence group (n=42) and non-recurrence group (n=42) according to whether the tumor recurred. Peripheral blood samples were collected on the day of diagnosis and 1, 3, 6 months after recurrence. ATP content in CD4+ T lymphocytes was detected using ImmuKnowTM immune cell function assay kit, subgroup counts were detected using IOTest. Results ATP content of CD4+ T lymphocytes in patients with liver cancer recurrence after liver transplantation was significantly lower than that in patients without recurrence at the day of diagnosis of recurrence, and 1, 3, 6 months after recurrence (P
Databáze: OpenAIRE