Antihyperglycemic and Hypoglycemic Effect of Ficus racemosa Leaves
| Autor: | Vikas V. Patil, N. G. Sutar, R. B. Pimprikar, A. P. Patil, R. Y. Chaudhari, V. R. Patil |
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| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: | |
| Zdroj: | Journal of Natural Remedies, Vol 10, Iss 1, Pp 11-16 (2010) |
| ISSN: | 2320-3358 0972-5547 |
| Popis: | Objective: To investigate the hypoglycemic and antihyperglycemic effects of an ethanolic extract of the leaves of Ficus racemosa in both normal and alloxan induced diabetes in rats. Materials and Methods: Blood samples were collected from the retro-orbital plexus under light ether anesthesia before and at 0.5, 1, 2, 4, 6, 8 and 12 h after the oral administration of 100, 200, and 300 /kg doses. Blood glucose was analyzed by glucose-oxidase method using a visible spectrophotometer. Results: Graded doses of the alcoholic extract when given to both normal and diabetic rats produce significant reductions in blood glucose at the 6 h after ethanolic extract administration (P < 0.001). The effect was found to be dose dependent with all treatments at the doses administered. Conclusion: The present study clearly indicated a significant antidiabetic activity of the leaves of Ficus racemosa and supports the traditional usage of fruits by the Ayurvedic physicians for the control of diabetes. |
| Databáze: | OpenAIRE |
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