| Autor: |
Bernot, G., Guespin, J., Comet, J.-P., Amar, P., Zemirline, A., Delaplace, F., Ballet, P., Richard, A. |
| Přispěvatelé: |
Zemirline, Abdallah, Amar, Képès, Norris and Tracqui Eds |
| Jazyk: |
angličtina |
| Rok vydání: |
2003 |
| Předmět: |
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| Popis: |
We propose an new methodology for modelling of biological regulatory networks inspired by the design and validation of large computing systems. We take into account the capability to validate a model by a set of biological experiments. So defining a model goes with experimental methods and conditions to validate or invalidate it. As in the design of large sized softwares, we will distinguish two activities: first to build an accurate model specifying the assumed behaviour, second to design plans of experiments to verify a posteriori the model predictions. We wish to experiment, through the case of the modelling of the mucus production by the bacterium Pseudomonas aeruginosa, the application of this working methodology. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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