Colchicine-induced neuromyopathy in a patient with chronic renal failure: the role of clarithromycin
Autor: | Velden, W. van der, Huussen, J., Laak, H.J. ter, Sevaux, R.G.L. de |
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Rok vydání: | 2008 |
Předmět: | |
Zdroj: | Netherlands Journal of Medicine, 66, 5, pp. 204-6 Netherlands Journal of Medicine, 66, 204-6 |
ISSN: | 0300-2977 |
Popis: | Item does not contain fulltext Neuromyopathy is a rare side effect of chronic colchicine therapy, most often occurring in patients with chronic renal failure. Drugs interacting with colchicine metabolism through CYP(3)A(4) and P-glycoprotein can accelerate accumulation and toxicity. We describe a case of an interaction between clarithromycin and colchicine resulting in acute neuromyopathy, and we conclude that combined use of macrolides and colchicine should be avoided. |
Databáze: | OpenAIRE |
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