EFFECT OF LINOPIRDINE ON FORCED SWIMMING TEST IN RATS

Autor:	Uzunok, Baris, Kahveci, Nevzat, Suyen, Guldal Gulec, Buyukuysal, M. Cagatay
Přispěvatelé:	Zonguldak Bülent Ecevit Üniversitesi, Uşak Üniversitesi
Jazyk:	turečtina
Rok vydání:	2019
Předmět:	forced-swim test depression Linopirdine potassium channels
Popis:	WOS: 000467534400006 Objective: In this study, we aimed to investigate the effect of Kv7 type voltage-gated potassium channel blocker linopirdin in Forced Swimming Test (FST) in rats. Material and Method: For this purpose, on the second day of the swimming test, rats received %0.9 NaCl (4 mu l) or a Kv7 type voltage-gated potassium channel blocker linopirdine (0.1, 1, 10 mu g/4 mu l) intracerebroventricularly (i.c.v.), 15 min before the test. Results: Linopirdine at a dose of 0.1 mu g/4 mu l significantly decreased immobilisation (p=0.003) and significantly increased swimming (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f7d18f2940621af6e34d8bf0bc044ef8 https://hdl.handle.net/20.500.12628/2455 Zobrazit plný text záznamu