Does hepatic visualisation show residual/metastatic thyroid tissue in differentiated thyroid cancer?
| Autor: | Hasbek, Zekiye, Gul, Serdar Savas, Ciftci, Esra, Erturk, Seyit Ahmet, Cakmakcilar, Ali, Duman, Gulhan, Turgut, Bulent |
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| Přispěvatelé: | [Hasbek, Zekiye -- Erturk, Seyit Ahmet -- Cakmakcilar, Ali] Cumhuriyet Univ, Sch Med, Dept Nucl Med, TR-58140 Sivas, Turkey -- [Gul, Serdar Savas] Gaziosmanpasa Univ, Sch Med, Dept Nucl Med, Tokat, Turkey -- [Ciftci, Esra] Sakarya Univ, Sch Med, Dept Nucl Med, Sakarya, Turkey -- [Duman, Gulhan] Cumhuriyet Univ, Sch Med, Dept Endocrinol, Sivas, Turkey -- [Turgut, Bulent] Katip Celebi Univ, Sch Med, Dept Nucl Med, Izmir, Turkey, CIFTCI, ESRA -- 0000-0001-6106-7733 |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: | |
| ISSN: | 0004-5187 |
| Popis: | WOS: 000451875800011 Aim: Diffuse homogen hepatic uptake in whole-body scan (WBS) after radioiodine remnant ablation (RRA) suggests that there is occult or visible remnant thyroid tissue and/or tumor tissue. It is thought that the reason is hepatic metabolization of radioiodine (1311) marked thyroglobulin fragments which are secreted by remnant/tumor tissue. The aims of this study were to investigate whether the hepatic visualisation after radioiodine remnant ablation showed the presence of metastatic or residual disease in patients with differentiated thyroid cancer and also to investigate whether early or late WBS after RRA (RxWBS) had an effect on the physiological hepatic uptake. Material and Method: 201 DTC patients were evaluated (F/M: 152/49; mean age: 49.61 +/- 13 years (range: 18-85 years)) who referred for RRA. The therapeutic 1311 dose ranged from 100mCi to 200mCi. RxWBS was performed earlier (in 1-4th-day after RRA) in 106 patients (Group 1) and was performed later (in 5-9th-day after RRA) in 95 patients (Group 2). Results: Diffuse hepatic uptake were seen only in three patients (2.8%) and was not seen in 103 patients (97.2%) in Group 1. However, in Group 2 diffuse hepatic uptake was seen in 93 patients (97.9%) (p |
| Databáze: | OpenAIRE |
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