| Autor: |
Bakır, Buket, Eliş Yıldız, Sevda, Karadağ Sarı, Ebru, Asker, Hasan, Nazli, Mumtaz |
| Přispěvatelé: |
MÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Nazlı, Mümtaz |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
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| Popis: |
WOS: 000374312100003 The purpose of this study was to investigate the effects of capsaicin on the duodenal distribution of cyclooxygenase-1 (COX-1), cyclooxygenase-2 (COX-2) and Transforming growth factor beta-1 (TGF beta-1) in rats. Rats were divided into two groups (n = 10 in each group). Experimental group treated with capsaicin (1 mg/kg, subcutaneously) was injected in 10% ethanol, 1% Tween and 80% distilled water everyday for a period of one week and in not injected control group. Localisations of COX-1, COX-2 and TGF beta-1 were observed in villus and crypt ephitelial cells, and smooth muscle cells. In conclusion, in this study, capsaicin administration was found to increase the release of COX-1 and COX-2, and TGF beta-1. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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