The value of routine follow-up after treatment for head and neck cancer. A national DAHANCA study

Autor: Pagh, Anja, Vedtofte, Thomas, Lynggaard, Charlotte Duch, Rubek, Niclas, Lonka, Matilde Mia Nis-Hansen, Johansen, Jørgen, Andersen, Elo, Kristensen, Claus Andrup, von Buchwald, Christian, Andersen, Maria, Godballe, Christian, Overgaard, Jens, Grau, Cai
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Pagh, A, Vedtofte, T, Lynggaard, C D, Rubek, N, Lonka, M M N-H, Johansen, J, Andersen, E, Kristensen, C A, von Buchwald, C, Andersen, M, Godballe, C, Overgaard, J & Grau, C 2013, ' The value of routine follow-up after treatment for head and neck cancer. A national DAHANCA study ', PhD day 2013, Aarhus, Denmark, 11/01/2013-11/01/2013 . < http://phd.au.dk/fileadmin/grads.au.dk/HE/PhD_Day_2013_Abstract_Book_01.pdf >
Popis: BACKGROUND: The post-treatment follow-up is well-integrated in the oncologic care tradition, based on the risk of developing recurrent disease or new primary tumors in treated patients. Furthermore, follow-up serves as an opportunity to monitor treatment effects and to provide clinical care of side effects. In this study we measured the activity and effectiveness of routine follow-up in head and neck cancer and assessed the value of follow-up from the perspectives of both physicians and the patients.PATIENTS AND METHODS: During a period of six weeks a prospective national cross section cohort of 619 patients attending regular follow-up were enrolled. All patients had received intended curative treatment for head and neck cancer and all were followed according to DAHANCA guidelines. Data were collected by the physician filling in a registration form containing chosen key parameters and patients filling in a validated questionnaire.RESULTS: The majority (91%) of the 619 visits was planned, and 75% of all visits included either tumor or treatment-related problems. Suspicion of recurrent disease led to further diagnostic work-up in 80 visits (13%). A total of 29 recurrences were found, and of these seven (25%) were asymptomatic, i.e. the "number needed to see" to detect one asymptomatic recurrence was 99. Treatment-related normal-tissue problems were addressed in 72% of all visits, and among these 18% required intervention. Although the majority of problems (either suspicion of recurrent disease or late effects) occurred within a few years after treatment, 39% of patients seen after three years also had problems. The majority of patients (97%) expressed satisfaction with the planned follow-up.CONCLUSION: Only few relapses are found in asymptomatic patients at routine follow-up, with one silent recurrence detected per 99 visits. However, head and neck cancer survivors have a substantial need for management of sequelae. In this context, a centralized routine follow-up may still be worthwhile.
Databáze: OpenAIRE