CO2-induced ocean acidification increases anxiety in rockfish via alteration of GABAA receptor functioning
| Autor: | Hamilton, Trevor James, Holcombe, Adam, Tresguerres, Martin |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Fish Proteins
Behavior Agricultural and Veterinary Sciences Muscimol GABA-A Animal Oceans and Seas Sebastes Environmental Exposure Carbon Dioxide Anxiety Hydrogen-Ion Concentration Biological Sciences Medical and Health Sciences Perciformes Pyridazines GABA Antagonists upwelling Receptors Animals Seawater gabazine GABA-A Receptor Agonists Life Below Water |
| Zdroj: | Hamilton, TJ; Holcombe, A; & Tresguerres, M. (2014). CO2-induced ocean acidification increases anxiety in rockfish via alteration of GABAA receptor functioning.. Proceedings. Biological sciences / The Royal Society, 281(1775), 20132509. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/0vp448hj Proceedings. Biological sciences, vol 281, iss 1775 Proceedings of the Royal Society B: Biological Sciences, vol 281, iss 1775 |
| Popis: | The average surface pH of the ocean is dropping at a rapid rate due to the dissolution of anthropogenic CO2, raising concerns for marine life. Additionally, some coastal areas periodically experience upwelling of CO2-enriched water with reduced pH. Previous research has demonstrated ocean acidification (OA)-induced changes in behavioural and sensory systems including olfaction, which is due to altered function of neural gamma-aminobutyric acid type A (GABAA) receptors. Here, we used a camera-based tracking software system to examine whether OA-dependent changes in GABAA receptors affect anxiety in juvenile Californian rockfish (Sebastes diploproa). Anxiety was estimated using behavioural tests that measure light/dark preference (scototaxis) and proximity to an object. After one week in OA conditions projected for the next century in the California shore (1125 ± 100 μatm, pH 7.75), anxiety was significantly increased relative to controls (483 ± 40 μatm CO2, pH 8.1). The GABAA-receptor agonist muscimol, but not the antagonist gabazine, caused a significant increase in anxiety consistent with altered Cl- flux in OA-exposed fish. OA-exposed fish remained more anxious even after 7 days back in control seawater; however, they resumed their normal behaviour by day 12. These results show that OA could severely alter rockfish behaviour; however, this effect is reversible. © 2013 The Author(s) Published by the Royal Society. All rights reserved. |
| Databáze: | OpenAIRE |
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