Restricted energy transfer in laser desorption of high molecular weight biomolecules

Autor:	Akos Vertes, Gijbels, R.
Jazyk:	angličtina
Rok vydání:	1991
Předmět:	ion formation energy transfer disintegration laser ionization biomolecules proteins nucleotides laser desorption phase transition fragmentation peptides saccharides Biology mass spectrometry nucleosides
Zdroj:	Scanning microscopy Scopus-Elsevier Scanning Microscopy
ISSN:	0891-7035
Popis:	Producing ions from large molecules is of distinguished importance in mass spectrometry. In our present study we survey different laser desorption methods in view of their virtues and drawbacks in volatilization and ion generation. Laser induced thermal desorption and matrix assisted laser desorption are assessed with special emphasis to the recent breakthrough in the field (m/z > 100,000 ions produced by matrix assisted laser desorption). Efforts to understand and describe laser desorption and ionization are also reported. We emphasize the role of restricted energy transfer pathways as a possible explanation to the volatilization of non-degraded large molecules.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::dee3d9dc18f8874c50c5a5fad157e376 https://hdl.handle.net/10067/7050151162165141 Zobrazit plný text záznamu