Linear IgA and IgG bullous dermatosis

Autor: Fernandes, Karina de Almeida Pinto, Galvis, Kely Hernández, Gomes, Anndressa Camillo da Matta Setubal, Nogueira, Osvania Maris, Felix, Paulo Antônio Oldani, Vargas, Thiago Jeunon de Sousa
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Anais Brasileiros de Dermatologia v.91 n.5 suppl.1 2016
Anais brasileiros de dermatologia
Sociedade Brasileira de Dermatologia (SBD)
instacron:SBD
Anais Brasileiros de Dermatologia, Volume: 91, Issue: 5 Supplement 1, Pages: 32-34, Published: OCT 2016
Popis: Childhood linear immunoglobulin A dermatosis is a rare autoimmune vesiculobullous disease. It results in linear deposition of autoantibodies (immunoglobulin A) against antigens in the basal membrane zone, leading to subepidermal cleavage. Additional depositions of immunoglobulin G and complement-3 might occur. It is still debated whether concomitant findings of immunoglobulins A and G should be considered a subtype of this dermatosis or a new entity. Further studies are needed to recognize this clinical variant.
Databáze: OpenAIRE