Theory of mind impairments in patients with semantic dementia
| Autor: | Duval, Céline, Bejanin, Alexandre, Piolino, Pascale, Laisney, Mickael, de La Sayette, Vincent, Belliard, Serge, Eustache, Francis, Desgranges, Béatrice |
|---|---|
| Přispěvatelé: | Neuropsychologie cognitive et neuroanatomie fonctionnelles de la mémoire humaine, Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire de Psychologie et Neurosciences Cognitives (LPNCog / UMR 8189), Université Paris Descartes - Paris 5 (UPD5)-Centre National de la Recherche Scientifique (CNRS), Service de Neurologie [CHU Caen], Normandie Université (NU)-Normandie Université (NU)-CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-Tumorothèque de Caen Basse-Normandie (TCBN), Service de neurologie [Rennes], Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES), Normandie Université (NU)-Normandie Université (NU)-École Pratique des Hautes Études (EPHE), Université de Rennes (UR) |
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
MESH: Aged
MESH: Theory of Mind MESH: Attention MESH: Humans MESH: Middle Aged cognitive/affective theory of mind imaging MESH: Neuropsychological Tests MESH: Atrophy MESH: Male objective/subjective assessment MESH: Executive Function semantic dementia MESH: Temporal Lobe [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC] MESH: Frontotemporal Lobar Degeneration MESH: Memory MESH: Female |
| Zdroj: | Brain-A Journal of Neurology Brain-A Journal of Neurology, Oxford University Press (OUP), 2012, 135 (Pt 1), pp.228-41. ⟨10.1093/brain/awr309⟩ Brain-A Journal of Neurology, 2012, 135 (Pt 1), pp.228-41. ⟨10.1093/brain/awr309⟩ |
| ISSN: | 0006-8950 1460-2156 |
| DOI: | 10.1093/brain/awr309⟩ |
| Popis: | International audience; Semantic dementia is characterized by semantic deficits and behavioural abnormalities that occur in the wake of bilateral inferolateral and predominantly left-sided anterior temporal lobe atrophy. The temporal poles have been shown to be involved in theory of mind, namely the ability to ascribe cognitive and affective mental states to others that regulates social interactions by predicting and interpreting human behaviour. However, very few studies have examined theory of mind in semantic dementia. In this study, we investigated both cognitive and affective theory of mind in a group of patients with semantic dementia, using separate objective and subjective assessment tasks. Results provided objective evidence of an impact of semantic dementia on cognitive and affective theory of mind, consistent with the patients' atrophy in the left temporal lobe and hypometabolism in the temporal lobes and the medial frontal cortex. However, the subjective assessment of theory of mind suggested that awareness of the affective but not cognitive theory of mind deficit persists into the moderate stage of the disease. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|