Regional sympathetic denervation affects the relation between canine local myocardial blood flow and oxygen consumption
Autor: | Alders, D., Cornelussen, R.N., Prinzen, F.W., Specht, P.A.C., Noble, M.J., Drake-Holland, A.J., de Kanter, F.J.J., van der Beek, J.P. |
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Přispěvatelé: | Organic Chemistry, Faculty of Sciences |
Jazyk: | angličtina |
Rok vydání: | 2007 |
Předmět: | |
Zdroj: | Experimental Physiology, 92, 541-548. Wiley-Blackwell Alders, D, Cornelussen, R N, Prinzen, F W, Specht, P A C, Noble, M J, Drake-Holland, A J, de Kanter, F J J & van der Beek, J P 2007, ' Regional sympathetic denervation affects the relation between canine local myocardial blood flow and oxygen consumption ', Experimental Physiology, vol. 92, pp. 541-548 . https://doi.org/10.1113/expphysiol.2006.036228 |
ISSN: | 0958-0670 |
DOI: | 10.1113/expphysiol.2006.036228 |
Popis: | Myocardial blood flow and oxygen consumption are heterogeneously distributed. Perfusion and myocardial oxygen consumption are closely correlated in the normal heart. It is unknown how this metabolism-perfusion relation is influenced by sympathetic denervation. We investigated this question in seven chloralose-anaesthetized dogs, 3-4 weeks after regional sympathetic denervation of the left circumflex coronary artery area of supply of the left ventricle. Measurements were made of local myocardial blood flow (MBF, in ml min |
Databáze: | OpenAIRE |
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