Possible artemisinin-based combination therapy-resistant malaria in Nigeria: a report of three cases

Autor:	Ajayi,Nnennaya Anthony, Ukwaja,Kingsley Nnanna
Jazyk:	angličtina
Rok vydání:	2013
Předmět:	Early treatment failure parasitic diseases Resistance Nigeria Artemether-lumefantrine Artemisinin-based combination therapy Malaria
Zdroj:	Revista da Sociedade Brasileira de Medicina Tropical, Volume: 46, Issue: 4, Pages: 525-527, Published: JUL 2013 Revista da Sociedade Brasileira de Medicina Tropical v.46 n.4 2013 Revista da Sociedade Brasileira de Medicina Tropical Sociedade Brasileira de Medicina Tropical (SBMT) instacron:SBMT
Popis:	Artemisinin-based combination therapy-resistant malaria is rare in Sub-Saharan Africa. The World Health Organization identifies monitoring and surveillance using day-3 parasitaemia post-treatment as the standard test for identifying suspected artemisinin resistance. We report three cases of early treatment failure due to possible artemisinin-based combination therapy-resistant Plasmodium falciparum malaria. All cases showed adequate clinical and parasitological responses to quinine. This study reveals a need to re-evaluate the quality and efficacy of artemisinin-based combination therapy agents in Nigeria and Sub-Saharan Africa.
Databáze:	OpenAIRE
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