Prevention of disease progression by cardiac resynchronization therapy in patients with asymptomatic or mildly symptomatic left ventricular dysfunction: insights from the European cohort of the REVERSE (Resynchronization Reverses Remodeling in Systolic Left Ventricular Dysfunction) trial

Autor: Daubert, C, Gold, MR, Abraham, WT, Ghio, S, Hassager, C, Goode, G, Szili-Torok, T (Tamás), Linde, C
Přispěvatelé: Service de cardiologie et maladies vasculaires, Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Hôpital Pontchaillou-CHU Pontchaillou [Rennes], Division of cardiology, Medical University of South Carolina [Charleston] (MUSC), Fondazione IRCCS Policlinico San Matteo [Pavia], Università di Pavia, Rigshospitalet [Copenhagen], Copenhagen University Hospital, Department of Cardiology, Karolinska University Hospital, Karolinska Institutet [Stockholm], REVERSE Study Group, Service de cardiologie et maladies vasculaires [Rennes] = Cardiac, Thoracic, and Vascular Surgery [Rennes], CHU Pontchaillou [Rennes], Cardiology
Jazyk: angličtina
Rok vydání: 2009
Předmět:
genetic structures
cardiac resynchronization therapy
heart failure
MESH: Cardiac Pacing
Artificial

MESH: Ventricular Remodeling
MESH: Hospitalization
MESH: Defibrillators
Implantable

[INFO.INFO-TS]Computer Science [cs]/Signal and Image Processing
[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system
MESH: Ventricular Dysfunction
Left

cardiovascular diseases
MESH: Treatment Outcome
MESH: Aged
MESH: Middle Aged
MESH: Humans
reverse cardiac remodeling
MESH: Follow-Up Studies
MESH: Male
MESH: Prospective Studies
randomized controlled trial
MESH: Heart Failure
cardiovascular system
biventricular stimulation
MESH: Disease Progression
[SDV.IB]Life Sciences [q-bio]/Bioengineering
MESH: Europe
MESH: Female
[SPI.SIGNAL]Engineering Sciences [physics]/Signal and Image processing
Zdroj: Journal of the American College of Cardiology
Journal of the American College of Cardiology, Elsevier, 2009, 54 (20), pp.1837-46. ⟨10.1016/j.jacc.2009.08.011⟩
Journal of the American College of Cardiology, 54(20), 1837-1846. Elsevier Inc.
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2009.08.011⟩
Popis: Objectives The aim of this study was to determine the long-term effects of cardiac resynchronization therapy (CRT) in the European cohort of patients enrolled in the REVERSE (Resynchronization Reverses Remodeling in Systolic Left Ventricular Dysfunction) trial. Background Previous data suggest that CRT slows disease progression and improves the outcomes of asymptomatic or mildly symptomatic patients with left ventricular (LV) dysfunction and a wide QRS complex. Methods We randomly assigned 262 recipients of CRT pacemakers or defibrillators, with QRS >= 120 ms and LV ejection fraction
Databáze: OpenAIRE