Effect of porous titanium coating thickness on in vitro osteoblast phenotype expression
| Autor: | Canabarro, Antonio, Crippa, Grasiele E., Shirozaki, Mariana U., Sampaio, Eduardo M., Lefebvre, Louis-Philippe, Oliveira, Paulo T., Beloti, Marcio M., Adalberto Luiz Rosa |
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| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: | |
| Zdroj: | Journal of Osseointegration, Vol 3, Iss 1, Pp 17-23 (2011) Web of Science |
| ISSN: | 2036-4121 |
| Popis: | Aim: This study aimed at determining the effect of different thickness of porous titanium (Ti) coating, 0.5, 1.0 and 1.5 mm thick (PC-0.5, PC-1.0 and PC-1.5), on osteoblast phenotype expression. Materials and methods: Dense Ti discs coated with 0.5, 1.0 and 1.5 mm of porous Ti (PC-0.5, PC-1.0 and PC-1.5, respectively) were fabricated by powder metallurgy process with pore size typically between 50 and 400 μm and porosity of 60%. Osteoblastic cells obtained from human alveolar bone were cultured on dense Ti (D-Ti) and PC-Ti discs for periods of up to 17 days. Results: Cultures grown on PC-Ti exhibited higher cell proliferation rate than on D-Ti. By comparing PC-Ti groups, it was observed statistical differences on culture grown only at day 10 (PC-0.5 |
| Databáze: | OpenAIRE |
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