Air pollution, blood pressure, and the risk of hypertensive complications during pregnancy: The generation r study

Autor: Hooven, E.H. van den, Kluizenaar, Y. de, Pierik, F.H., Hofman, A., Ratingen, S.W. van, Zandveld, P.Y.J., MacKenbach, J.P., Steegers, E.A.P., Miedema, H.M.E., Jaddoe, V.W.V.
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Hypertension, 3, 57, 406-412
Popis: Exposure to air pollution is associated with elevated blood pressure and cardiovascular disease. We assessed the associations of exposure to particulate matter (PM10) and nitrogen dioxide (NO2) levels with blood pressure measured in each trimester of pregnancy and the risks of pregnancy-induced hypertension and preeclampsia in 7006 women participating in a prospective cohort study in the Netherlands. Information on gestational hypertensive disorders was obtained from medical records. PM10 exposure was not associated with first trimester systolic and diastolic blood pressure, but a 10-µg/m increase in PM10 levels was associated with a 1.11-mm Hg (95% confidence interval [CI] 0.43 to 1.79) and 2.11-mm Hg (95% CI 1.34 to 2.89) increase in systolic blood pressure in the second and third trimester, respectively. Longitudinal analyses showed that elevated PM10 exposure levels were associated with a steeper increase in systolic blood pressure throughout pregnancy (P
Databáze: OpenAIRE