| Autor: |
Jansen, Tom, Geleijnse, Gijs, van Maaren, Marissa, Hendriks, Mathijs P., Ten Teije, Annette, Moncada-Torres, Arturo |
| Přispěvatelé: |
Pape-Haugaard, Louise B., Lovis, Christian, Madsen, Inge Cort, Weber, Patrick, Nielsen, Per Hostrup, Scott, Philip |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Jansen, T, Geleijnse, G, van Maaren, M, Hendriks, M P, Ten Teije, A & Moncada-Torres, A 2020, Machine learning explainability in breast cancer survival . in L B Pape-Haugaard, C Lovis, I C Madsen, P Weber, P H Nielsen & P Scott (eds), Digital Personalized Health and Medicine : Proceedings of MIE 2020 . Studies in Health Technology and Informatics, vol. 270, IOS Press, pp. 307-311, 30th Medical Informatics Europe Conference, MIE 2020, Geneva, Switzerland, 28/04/20 . https://doi.org/10.3233/SHTI200172 |
| ISSN: |
0926-9630 |
| DOI: |
10.3233/shti200172 |
| Popis: |
Machine Learning (ML) can improve the diagnosis, treatment decisions, and understanding of cancer. However, the low explainability of how “black box” ML methods produce their output hinders their clinical adoption. In this paper, we used data from the Netherlands Cancer Registry to generate a ML-based model to predict 10-year overall survival of breast cancer patients. Then, we used Local Interpretable Model-Agnostic Explanations (LIME) and SHapley Additive exPlanations (SHAP) to interpret the model's predictions. We found that, overall, LIME and SHAP tend to be consistent when explaining the contribution of different features. Nevertheless, the feature ranges where they have a mismatch can also be of interest, since they can help us identifying “turning points” where features go from favoring survived to favoring deceased (or vice versa). Explainability techniques can pave the way for better acceptance of ML techniques. However, their evaluation and translation to real-life scenarios need to be researched further. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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