Autor:	ELİYATKIN, NUKET, ERÇETİN, AYŞE PINAR, KÜPELİOĞLU, ALİ, ÖZGÜR, HAKAN, AKTAŞ, SAFİYE
Jazyk:	angličtina
Rok vydání:	2016
Popis:	Purpose: Trastuzumab, the HER2 oncogene targeting drug, shows remarkable clinical efficacy in HER2-amplified breast cancer patients. Despite of robust activity, some of the patients with HER2-positive breast cancers do not get the benefit due to trastuzumab resistance. Overexpression of p95HER2 is one of the molecular mechanisms of trastuzumab resistance. The purpose of this study was to investigate whether p95HER2 overexpressing breast cancers were resistant to trastuzumab.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::cd67d8136d01f612b932a5d56e71a7ef https://avesis.deu.edu.tr/publication/details/0fe55214-de74-44b0-a320-ea6d9e46b100/oai Zobrazit plný text záznamu