Brazilian Journal of Medical and Biological Research

Autor: Nora, Daniel Bocchese, Gomes, I., Said, G., Carvalho, F. M., Melo, Ailton de Souza
Jazyk: angličtina
Rok vydání: 2007
Předmět:
Zdroj: Brazilian Journal of Medical and Biological Research, Vol 40, Iss 1, Pp 81-87 (2007)
Repositório Institucional da UFBA
Universidade Federal da Bahia (UFBA)
instacron:UFBA
Brazilian Journal of Medical and Biological Research, Volume: 40, Issue: 1, Pages: 81-87, Published: JAN 2007
Brazilian Journal of Medical and Biological Research v.40 n.1 2007
Brazilian Journal of Medical and Biological Research
Associação Brasileira de Divulgação Científica (ABDC)
instacron:ABDC
ISSN: 0100-879X
DOI: 10.1590/S0100-879X2007000100011
Popis: p. 81-87 Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2014-03-12T14:05:54Z No. of bitstreams: 1 0100-879X2007000100011.pdf: 471976 bytes, checksum: 8730c69bee7be44e04c80e2c01cbaddf (MD5) Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2014-09-09T14:50:03Z (GMT) No. of bitstreams: 1 0100-879X2007000100011.pdf: 471976 bytes, checksum: 8730c69bee7be44e04c80e2c01cbaddf (MD5) Made available in DSpace on 2014-09-09T14:50:03Z (GMT). No. of bitstreams: 1 0100-879X2007000100011.pdf: 471976 bytes, checksum: 8730c69bee7be44e04c80e2c01cbaddf (MD5) Previous issue date: 2007 The long-term effects of low-level lead intoxication are not known. The sympathetic skin response (SSR) was evaluated in a group of 60 former workers of a primary lead smelter, located in Santo Amaro, BA, Brazil. The individuals participating in the study were submitted to a clinical-epidemiological evaluation including questions related to potential risk factors for intoxication, complaints related to peripheral nervous system (PNS) involvement, neurological clinical examination, and also to electromyography and nerve conduction studies and SSR evaluation. The sample consisted of 57 men and 3 women aged 34 to 69 years (mean ± SD: 46.8 ± 6.9). The neurophysiologic evaluation showed the presence of lumbosacral radiculopathy in one of the individuals (1.7%), axonal sensorimotor polyneuropathy in 2 (3.3%), and carpal tunnel syndrome in 6 (10%). SSR was abnormal or absent in 12 cases, representing 20% of the sample. More than half of the subjects (53.3%) reported a history of acute abdominal pain requiring hospitalization during the period of work at the plant. A history of acute palsy of radial and peroneal nerves was reported by about 16.7 and 8.3% of the individuals, respectively. Mean SSR amplitude did not differ significantly between patients presenting or not the various characteristics in the current neurological situation, except for diaphoresis. The results suggest that chronic lead intoxication induces PNS damage, particularly affecting unmyelinated small fibers. Further systematic study is needed to more precisely define the role of lead in inducing PNS injury.
Databáze: OpenAIRE
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