Antitumoral effect of Non Thermal Plasmas produced by a Plasma Gun: Plasma treatment alone or in combination with chemotherapy

Autor: Brullé, Laura, Vandamme, Marc, Robert, Eric, Sarron, Vanessa, Riès, Delphine, Dozias, Sébastien, Lerondel, Stéphanie, Le Pape, Alain, Pouvesle, Jean Michel
Přispěvatelé: Trangenèse et archivage d'animaux modèles, Centre d'Imagerie du Petit Animal (CIPA), Université d'Orléans (UO)-Université d'Orléans (UO), Groupe de recherches sur l'énergétique des milieux ionisés (GREMI), Centre National de la Recherche Scientifique (CNRS)-Université d'Orléans (UO), Transgénèse et Archivage d'Animaux Modèles - Centre d'Imagerie du Petit Animal (TAAM-CIPA), Centre National de la Recherche Scientifique (CNRS), Centre d'Etude des Pathologies Respiratoires, Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Robert, Eric
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: HTPP12
HTPP12, Jun 2012, bologna, Italy
Popis: International audience; Cancer of the exocrine pancreas, especially ductal adenocarcinoma, the most common pancreatic cancer, is rarely curable and has an overall survival rate of less than 4%. Moreover, chemotherapy and radiotherapy of pancreatic cancer are only, up to now, palliative treatments. New therapeutic approaches are then necessary. Recent results were obtained on the treatment of heterotopic glioblastoma2 and colon carcinoma3, and orthotopic colon carcinoma (Figure 1) using non thermal plasma (NTP). They led us to assess the antitumoral effect of NTP alone or in combination with Gemcitabine, a reference chemotherapeutic agent with radiosensitizing properties, on pancreatic cancer.
Databáze: OpenAIRE