Mesterolone treatment of aging male syndrome improves lower urinary tract symptoms

Autor: Seven, Ismet, Ozturk, Mustafa, Atmaca, Murat, Dugeroglu, Harun
Přispěvatelé: Dugeroglu, Harun, Seven, Ismet Yuzuncu Yil Univ, Fac Med, Dept Internal Med, Van, Turkey, Atmaca, Murat Yuzuncu Yil Univ, Fac Med, Dept Endocrinol & Metab, Van, Turkey, Ozturk, Mustafa Medipol Univ, Fac Med, Dept Endocrinol & Metab, Istanbul, Turkey
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Popis: WOS: 000346551200008 PubMed ID: 25842579 Objective: To investigate the effects of mesterolone on prostate in patients treated for aging male syndrome. Methods: The cross-sectional study was conducted from June to September, 2009, at endocrinology and metabolism department of Yuzuncu Yil University, Van, Turkey, and comprised patients with symptoms of aging male syndrome and/or low testosterone. They were given mesterolone 50mg/day per oral for two months. Aging Male Symptoms and International Prostate Symptom Score questionaires and prostate-related quality of life scores were completed and prostate ultrasonography (USG) was performed before and after the treatment. Total testosterone, free testosterone, gonadotropins, estradiol, prolactin, sex-hormone binding globulin, as well as total and free prostate-specific antigen were also studied. Results: Of the 34 patients in the study, 22(64.70%) had their prostate volume increased, while 12(35.29%) had it decreased. The change, however, was not statistically significant (p
Databáze: OpenAIRE