| Autor: |
De Berardinis, P, Londei, M, Kahan, M, Balsano, F, Kontiainen, S, Gale, EA, Bottazzo, GF, Feldmann, M |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Popis: |
Twenty-five recently diagnosed insulin-dependent diabetic patients were screened for the presence of activated T lymphocytes using the anti-IL-2 receptor monoclonal antibody; thirteen had elevated levels of activated T lymphocytes. The activated cells were mostly confined to the CD4 subset, with the CD4/CD8 ratio in IL-2 receptor expressing cells averaging 5 +/- 1 (s.d.) compared with 1.3 +/- 0.3 for all T cells. In recent onset insulin-dependent diabetes blood there was no lack of CD4 CD45R+ (suppressor/inducer) T cells. The activated IL-2 receptor, expressing cells belonged to both CD4 subsets, 'helper inducer' (CD44B4) and 'suppressor inducer', (CD42H4). |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
